MARYLAND INDUSTRIAL PARTNERSHIPS

MIPS Projects

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MIPS Round 

50

August

 

2012

August 1, 2012

20/20 GeneSystems, Inc.

Rockville

 | 

Montgomery

 County

Project:

MicroRNA As A Blood Analyte For Lung Cancer

Principal Investigator:

Feng
 
Jiang
Associate Professor

Technologies:

Biotechnology / Genetic Engineering

20/20 GeneSystems was founded to develop and promote an innovative proteomics product line that provides drug companies, biodefense specialists and life scientists with new tools for protein analysis. The company’s first product, and the focus of the company’s work through MIPS, called BioCheck®, is the “gold standard” test for the screening of unknown suspicious powders by emergency personnel and first responders.  Since developing BioCheck, the company has expanded its scope to developing and commercializing innovative, proprietary diagnostic tests that aid in the fight against cancer. These tests generally fall into three categories: personalized medicine, early detection of lung cancer, and biological detection.

MIPS Round 

50

August

 

2012

August 1, 2012

Biomedica Management Corp

Baltimore

 | 

Baltimore

 County

Project:

Optimization of Novel Hemostatic Agent ClotBlock

Principal Investigator:

Leonid
 
Medved
Professor

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

50

August

 

2012

August 1, 2012

Zuvachem, Inc.

Lutherville

 | 

Baltimore

 County

Project:

Enhanced microbial production of isoprene

Principal Investigator:

Frank
 
Robb
Professor

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

50

August

 

2012

August 1, 2012

Syntonics LLC

Columbia

 | 

Howard

 County

Project:

MEMS Components for PARCA Software-Defined Antenna

Principal Investigator:

Don
 
DeVoe
Professor, Department of Mechanical Engineering

Technologies:

Communications

Syntonics innovates and manufactures specialty RF communications equipment and accessories, especially RF-over-fiber products and innovative antennas, for military, civil and industrial markets.

The company’s PARCA (Pixel-Addressable Reconfigurable Conformal Antenna) is a phased array technology that operates under software control to be pointing-agile, frequency-agile, polarization-agile, lowprofile, and affordable. The PARCA concept uses a dense array of conductive pixels that can be turned ‘on’ or ‘off’ to rapidly (one millisecond) reconfigure a patch array’s beam pointing direction, operating frequency, aperture gain, and beam polarization.

A new type of out-of-plane electrostatic microactuator delivering exceptionally high vertical displacements was developed. The performance of various actuator designs was characterized and shown to be in good agreement with analytical predictions. Fabricated microstage actuators achieving deflections up to 60 percent of their in-plane dimensions were realized, and reliable actuation over nearly 10 million cycles was demonstrated.

At the same time, a microfabrication process was developed for manufacturing low-mass antenna pixels comprising two conductive layers on either side of a thick polymer matrix. Individual pixels were successfully fabricated, and a process supporting integration of the pixels with zipper microactuators was conceived.

The following paper was submitted for publication as a result of this MIPS project: J. Felder, E. Lee, D.L. DeVoe, “Extreme vertical displacement electrostatic zipper microstage actuators,” submitted to J. MEMS, 2013.

MIPS Round 

50

August

 

2012

August 1, 2012

InstantLabs Medical Diagnostics Corporation

Baltimore

 | 

Baltimore City

 County

Project:

Development of PCR assay for the detection of MRSA

Principal Investigator:

Jennifer Kristie
 
Johnson
Professor, Pathology

Technologies:

Medical Instrumentation / Equipment

InstantLabs is a molecular diagnostic device company and the developer of portable, quantitative, real-time PCR (qPCR) systems. The company is focused on medical diagnostic and food safety applications for its proprietary technologies. InstantLabs currently markets its Hunter Accelerated-PCR® platform with disposable Multiple Assay Cartridges (MACs), bringing simplicity and power to complex diagnostic testing without dependency on central laboratories or acute-care facilities for sample analysis. The compact, affordable and fully-integrated Hunter system is especially suited for use at points-of-care and points-of-need to detect and analyze a wide variety of common and problematic pathogens. InstantLabs is positioned to broaden the addressable market for RT-PCR in areas where gold-standard accuracy, combined with ease-of-use and rapid time to results, can make a consequential improvement in operational efficiency, as well as health outcomes.

The quality of the researchers and the support from MIPS will allow us to enter the market sooner.
InstantLabs’ instrument, the Hunter, is not confined to human diagnostics. It is also used in food safety, food fraud, and industrial corrosion applications.

MIPS Round 

50

August

 

2012

August 1, 2012

AHPharma Food Safety Products, Inc.

Salisbury

 | 

Wicomico

 County

Project:

Radiant & Manure Burning Heat System NH3 Control

Principal Investigator:

Jennifer
 
Timmons
Associate Professor

Technologies:

Agriculture / Poultry Science

Energy

Environmental Technology / Science

The mission of AHPharma is to conduct private research for the agriculture industry and reinvest in the core business of the design, development, and commercialization of new technologies for improving animal agriculture production, nutrition, health, energy savings and housing techniques.

AHPharma’s radiant floors are designed to provide heat closer to bird activity via hot-water piping. By only emitting heat where it is needed, growers can reduce propane usage by up to 75 percent.

The company’s LED lighting system for poultry houses, called AviLighting®, reduces energy cost for growers by up to 94 percent per year over incandescent bulbs.

The Radiant & Manure Burning Heat System, (funded by MIPS-DNR), provided an efficiently engineered, cost-effective prototype that the poultry industry will be able to employ within the normal grow-out system, without disruption to normal BMPs (best management practices). The system is being reviewed by national environmental agencies as a method of improving animal welfare, human-worker welfare and grower profitability as well as reduce atmospheric ammonia releases from chicken-rearing houses.

MIPS provides an avenue for the poultry industry to get on a path of sustainable agriculture, produce energy savings that result in quick payback and significant grower profits, provide technology needed to meet EPA regulations to have a positive impact on Chesapeake Bay Restoration, and provide a much-needed boost in the Maryland jobs market, not only in the manufacturing of new technology systems, but in the marketing, installation, and maintenance of these systems as well.

MIPS Round 

50

August

 

2012

August 1, 2012

Innovative Bios

Baltimore

 | 

Baltimore

 County

Project:

Renewable Cell Culture Broth

Principal Investigator:

Ryan
 
Casey
Associate Professor

Technologies:

Chemical Engineering / Chemistry

MIPS Round 

50

August

 

2012

August 1, 2012

Leadership Health LLC

Leonardtown

 | 

Saint Mary’s

 County

Project:

Enabling the Expansion of Physical Therapy Clinics

Principal Investigator:

Jae Kun
 
Shim
Assistant Professor

Technologies:

Bio / Med / Health InfoTech

MIPS Round 

49

February

 

2012

February 1, 2012

CSA Medical

Lutherville

 | 

Baltimore City

 County

Project:

Spray Cryotherapy for Esophageal Cancer

Principal Investigator:

Bruce
 
Greenwald
Professor of Medicine

Technologies:

Medical Instrumentation / Equipment

MIPS Round 

49

February

 

2012

February 1, 2012

Under Armour

Baltimore

 | 

Baltimore City

 County

Project:

Running Adaptation to a New Shoe Design

Principal Investigator:

Jae Kun
 
Shim
Assistant Professor, Kinesiology

Technologies:

Other

Under Armour® (NYSE: UA) is a leading developer, marketer and distributor of branded performance apparel, footwear and accessories. The company’s products are sold worldwide and worn by athletes at all levels, from youth to professionals, on playing fields around the globe. The Under Armour® global headquarters is in Baltimore, Md., with European headquarters in Amsterdam’s Olympic Stadium, and additional offices in Denver, Hong Kong, Toronto, and Guangzhou, China.

MIPS Round 

49

February

 

2012

February 1, 2012

Prasidiux, LLC

Bowie

 | 

Prince George’s

 County

Project:

Validation of Gel Based Temperature Sensors

Principal Investigator:

Srinivasa
 
Raghavan
Professor

Technologies:

Chemical Engineering / Chemistry

MIPS Round 

49

February

 

2012

February 1, 2012

Omic Biosystems, Inc.

Rockville

 | 

Montgomery

 County

Project:

DiART Enabled Proteomic Biomarker Discovery

Principal Investigator:

Mark
 
Marten
Professor

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

49

February

 

2012

February 1, 2012

Captain's Choice Inc.

Princess Anne

 | 

Somerset

 County

Project:

New thermal processing system for a small company

Principal Investigator:

Jurgen
 
Schwarz
Professor & Chair

Technologies:

Food Processing

MIPS Round 

49

February

 

2012

February 1, 2012

Beacon Research, Incorporated

Alexandria

 | 

out-of-state

 County

Project:

Geotextile Filtration of Stormwater

Principal Investigator:

Allen
 
Davis
Professor

Technologies:

Environmental Technology / Science

MIPS Round 

49

February

 

2012

February 1, 2012

Imagilin Technology, LLC

Frederick

 | 

Frederick

 County

Project:

Effects of probiotics on equine immune responses

Principal Investigator:

Martin
 
Furr
Professor, DVM

Technologies:

Agriculture / Poultry Science

MIPS Round 

49

February

 

2012

February 1, 2012

Spessard Manufacturing, LLC

Hagerstown

 | 

Washington

 County

Project:

Electronic Home Plate

Principal Investigator:

Christopher
 
Davis

Technologies:

Instrumentation

MIPS Round 

49

February

 

2012

February 1, 2012

HY-TEK Bio, LLC.

Dayton

 | 

Howard

 County

Project:

Clean Energy from Fossil Fuels using HY-TEK Bio.

Principal Investigator:

Feng
 
Chen
Professor

Technologies:

Energy

Environmental Technology / Science

HY-TEK Bio is an early stage company developing a patent-pending system to remove carbon dioxide and other harmful greenhouse gases from smoke stack flue gas using a unique strain of algae while producing valuable byproducts from the algae. The company’s system mitigates greenhouse gas from flue gases by injecting the flue gas into a tank full of a unique strain of algae. The tank is a patent-pending, closed bioreactor produced in-house from a lamination of Mylar and Kevlar. This patent-pending construct allows the bioreactors to be produced inexpensively while being extremely light weight. In addition, patent-pending LED Grow Lights are used along with a nutrient developed in-house, made from fresh chicken manure and a blend of other proprietary components.

The algae feeds on the CO2 and NOx in the flue gas, as well as on the nutrient. CO2 consumption is enhanced through the use of proprietary LED Grow Light technology, yielding minimal greenhouse gas emissions and high yields of high-value algal biomass. The process produces little to no CO2 or NOx emissions, while enhancing the lipid-oil production in the algae as well as a by-product of Lutein-Zeaxanthin, an ultra-antioxidant that is in high demand in the market place. The algal biomass can be sold to brokers, who place the biomass into markets that produce Lutein-Zeaxanthin-based products, bio-plastics, skin care products, cosmetic and paint thickeners, additives for human and animal food products, and biofuel.

We are moving to an entirely new concept in closed bioreactor design using our patentpending Mylar/Kevlar tank structure, our unique “modulated” LED Grow Light technology, our patent-pending air injection system and our special, high-value chicken manurebased nutrient. These concepts will revolutionize closed bioreactors and the way the world mitigates greenhouse gas emissions.
HY-TEK Bio is a classic example of the Maryland Industrial Partnerships Program making a difference in helping a small company bring big ideas to market.

MIPS Round 

49

February

 

2012

February 1, 2012

Whisker Labs

Germantown

 | 

Montgomery

 County

Project:

Building Models for Demand Response Energy Trading

Principal Investigator:

Jungho
 
Kim
Professor, Department of Mechanical Engineering

Technologies:

Energy

Whisker Labs has built an energy management platform, Connected SavingsSM, which is an intelligent demand side management (IDSM) system that ties homes with utilities, big weather data and analytics to save energy—for customers, utilities and retail energy providers. The solution combines connected thermostats with proprietary weather information and thermodynamic models, developed in part with the University of Maryland, that predict how homes will respond to changing weather conditions, thus correlating energy usage to weather. Homes can then be intelligently precooled and setback, keeping customers comfortable while shifting loads for utilities during peak load events (DR events).

Over several years and several studies, the Connected Savings solution has outperformed similar, competing energy demand-response products by 15-20 percent. Additionally, homes have seen a 10 percent average HVAC energy saving for participating homes through thermostat efficiency adjustments, often over $100 in savings. Recently, Whisker Labs was ranked as the #2 residential demand response provider in the prestigious Navigant Research Leaderboard: Residential Demand Response report.

Currently, over 100,000 customers across the U.S. are using Whisker Labs’ home energy system, while approximately 20 utility partners are using Connected Savings in Texas, California, New England, and Maryland.

Siemann joined Whisker Labs after graduating, as have an additional four previous UMD engineering graduate students. In addition, the Whisker Labs Connected Savings team has grown from four employees prior to the MIPS grant, to nearly 30 here in Maryland.

Starting in January, 2017, Whisker Labs commenced a new MIPS project with mechanical engineering Professor Steven Gabriel, to study the potential economic benefits of DR for retail energy providers through the use of the Connected Savings solution and advanced setpoint scheduling. The research team also still works closely with Professor Kim on advancing its HVAC Fault Detection and Diagnostics technology.

In addition, Whisker Labs has developed a new product that sits on breaker panels in homes, installs in minutes, can tell what appliances are running based upon their electronic signatures, and provides detailed insights about a home’s energy usage. The company anticipates that with this new technology, combined with connected thermostats, connected homes, proprietary weather data, home energy score cards and thermodynamic analytics developed with the University of Maryland in the Connected Savings solution, it will become the leading provider of demand-response energy savings in the nation.

We are fortunate to work with a great mechanical engineering group at the University of Maryland. MIPS funding allowed us to get into the market offering a novel approach to demand response challenges. Now that we have data certified by utilities and consumers like us, we are expecting to grow the program into a much larger initiative that will result in more skilled and well-paying jobs here in Maryland. MIPS funding was critical in taking the Connected Savings program from concept to reality.

MIPS Round 

49

February

 

2012

February 1, 2012

Luke's Premier Foods, LLC

Princess Anne

 | 

Somerset

 County

Project:

Scale-up process for Heirloom Tomato Juice

Principal Investigator:

Jurgen
 
Schwarz
Director

Technologies:

Food Processing

MIPS Round 

49

February

 

2012

February 1, 2012

Corridor Pharmaceuticals, Inc

Towson

 | 

Baltimore

 County

Project:

Arginase Inhibition in control of B. anthracis

Principal Investigator:

Gerald
 
Rosen
Professor

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

49

February

 

2012

February 1, 2012

BlueWing Environmental Solutions & Technologies, LLC

Parkton

 | 

Howard

 County

Project:

Using floating wetlands to remove N and P on CAFOs

Principal Investigator:

Joshua
 
McGrath
Assistant Professor

Technologies:

Environmental Technology / Science

MIPS Round 

49

February

 

2012

February 1, 2012

Plant Sensory Systems, LLC

Baltimore

 | 

Baltimore City

 County

Project:

Production of Nematode Resistant Soybean

Principal Investigator:

Nadim
 
Alkharouf
Associate Professor, Computer Sciences

Technologies:

Biotechnology / Genetic Engineering

Plant Sensory Systems LLC is a privately held agricultural biotechnology company that develops proprietary plant technologies for sustainable food, feed, fiber, biofuel and bio-based products. PSS has expertise in modifying plant metabolic pathways and selects those pathways with real commercial value to develop into high-value products. The company is located at bwtech@UMBC Research and Technology Park.

PSS is in discussion with several large seed companies regarding licensing opportunities and has received angel investments.

In December, 2012, PSS was awarded a $2.2 million grant for biofuel research from the U.S. Department of Energy’s Advanced Research Projects Agency-Energy (ARPA-E). In January, 2012, PSS was awarded U.S. Patent No. 8,106,261, which relates to the production of GABA in cells. Additional IP coverage for the technology was obtained in U.S. Patent Nos. 8,581,040 and 8,581,041, which were awarded in November, 2013, and U.S. Patent No. 9,487,792, which was awarded in November, 2016.

In June, 2014, the company was awarded U.S. Patent No. 8,742,204, which relates to the binding of metabolites in cells. In March, 2016, the company was awarded U.S. Patent No. 9,267,148, which relates to the production of taurine in cells with a biosynthetic pathway that, when moved into plants, can deliver taurine in its seeds. In April, 2017, the company was awarded a $750,000 NSF SBIR grant as a direct result of MIPS to use PSS’ biotechnology approach to increase the essential nutrients in soybean seeds for use in aquafeed.

As of August, 2017, PSS had six employees.

MIPS funding was the impetus in bringing together a team of talented plant scientists from the university, federal government and small business sectors to work together on a project that addresses a critical agronomic need. The positive results of the project substantially broaden the commercial potential of the tested PSS technology

MIPS Round 

49

February

 

2012

February 1, 2012

Instant Access Networks, LLC

Cumberland

 | 

Allegany

 County

Project:

Hydrogen Collection and Storage for Power Systems

Principal Investigator:

Mohammed
 
Eltayeb
Department Chair

Technologies:

Energy

MIPS Round 

48

August

 

2011

August 1, 2011

Biketoo

Fruitland

 | 

Wicomico

 County

Project:

Design and Development of Motorized Bicycles

Principal Investigator:

Chandrasekhar
 
Thamire
Principal Lecturer

Technologies:

Mechanical Machinery

Structural Analysis / Design

MIPS Round 

48

August

 

2011

August 1, 2011

Genovation Cars Inc

Rockville

 | 

Montgomery

 County

Project:

Aerodynamic Modeling of a High Efficiency Vehicle

Principal Investigator:

Jewel
 
Barlow
Director of Glenn L. Martin Wind Tunnel

Technologies:

Aerodynamics / Aerospace Engineering

Wind Tunnel / Rotor Testing

Genovation’s long-term goal is to be a premier provider of high-performance sustainable automobiles. The company is committed to advancing the state of the art in electrical vehicle (EV) technology with the knowledge that performance EVs will accelerate the delivery of sustainable products for future generations. Genovation’s GXE all-electric Corvette has broken several world records on multiple occasions. Through the development of the Genovation GXE Corvette, the company is raising the bar in energy storage, propulsion, composite and suspension technologies.

The GXE wind tunnel program is currently in progress.

In February, 2017, the Genovation GXE C6 supercar broke the world speed record for fastest street-legal electric super car (209 mph) for the third time in 12 months. The GXE includes a state-of-the-art battery management system, inverters, batteries and electric motors that exceed 700-hp and 600 lb-ft of torque. Through improvements in development, the range has been extended to 150 miles during normal driving operation. The GXE supercar is designed for superior handling, with a near 50/50 weight distribution and optimized for a low center of gravity.

Genovation is currently in the testing and development phase for its GXE C7 and has begun accepting preorders for 75 production vehicles.

The MIPS program will enable Genovation to achieve a critical success factor in the most cost-effective means possible. One of the biggest aspects related to automobile efficiency is air resistance. Typically, around 60 percent of the power required to cruise at highway speeds is used to overcome aerodynamic drag. This percentage increases the faster you go, as drag squares with speed (doubling speed increases drag four-fold). Automotive aerodynamics is also critically important for safety reasons, most notably to increase downforce. Great care is being taken to design the GXE with a healthy amount of downforce and aerodynamic stability.