MARYLAND INDUSTRIAL PARTNERSHIPS

MIPS Projects

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MIPS Round 

26

August

 

2000

August 1, 2000

Emergent ImmunoSolutions

Gaithersburg

 | 

Montgomery

 County

Project:

Airway Mucous Secretion Inhibitors

Principal Investigator:

Kwang
 
Kim

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

26

August

 

2000

August 1, 2000

Davon Crest Farm L.L.C.

Hurlock

 | 

Dorchester

 County

Project:

Small Fruit Breeding Program

Principal Investigator:

Harry
 
Swartz

Technologies:

Agriculture / Poultry Science

MIPS Round 

26

August

 

2000

August 1, 2000

Aither Engineering

Lanham

 | 

Prince George’s

 County

Project:

Fiber Optic Structural Monitoring

Principal Investigator:

Steven
 
Buckley

Technologies:

Instrumentation

MIPS Round 

26

August

 

2000

August 1, 2000

Northrop Grumman Corp

Baltimore

 | 

Baltimore

 County

Project:

LTCC Filters for Radar Application

Principal Investigator:

Kawthar
 
Zaki

Technologies:

Microwave

Northrop Grumman Corporation offers an extraordinary portfolio of capabilities and technologies that enable the company to deliver innovative systems and solutions for applications that range from undersea to outer space and into cyberspace.

The company’s core competencies address emerging global security challenges in key areas, such as unmanned systems, cybersecurity, C4ISR, and logistics that are critical to the defense of the nation and its allies.

MIPS Round 

26

August

 

2000

August 1, 2000

ProBiotix, Inc.

Adelphi

 | 

Prince George’s

 County

Project:

Scale-up and Toxicity of BioNexin

Principal Investigator:

Pinaki
 
Panigrahi

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

26

August

 

2000

August 1, 2000

Intelligent Automation, Inc.

Rockville

 | 

Montgomery

 County

Project:

Twin Screw Extruder

Principal Investigator:

David
 
Bigio
Professor

Technologies:

Mechanical Machinery

MIPS Round 

26

August

 

2000

August 1, 2000

Gordon Shellfish

Snow Hill

 | 

Worcester

 County

Project:

Seaside Bay Clam Farming

Principal Investigator:

Donald
 
Meritt
Principal Agent

Technologies:

Aquaculture

MIPS Round 

25

February

 

2000

February 1, 2000

Cylex Inc.

Columbia

 | 

Howard

 County

Project:

Assay System for Measuring Immune Reconstitution

Principal Investigator:

Robert
 
Redfield

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

25

February

 

2000

February 1, 2000

GIS-USA, Inc.

Edgewater

 | 

Anne Arundel

 County

Project:

GIS Training

Principal Investigator:

Derek
 
Thompson

Technologies:

Software Development

Other

MIPS Round 

25

February

 

2000

February 1, 2000

Energy Concepts Co., LLC

Annapolis

 | 

Anne Arundel

 County

Project:

Controller for Heat Pump

Principal Investigator:

M. Appa
 
Anjanappa
Professor

Technologies:

Controls

MIPS Round 

25

February

 

2000

February 1, 2000

WisdomBuilder, Inc.

Columbia

 | 

Howard

 County

Project:

Intelligent User Agent

Principal Investigator:

Jay
 
Liebowitz

Technologies:

Software Development

MIPS Round 

25

February

 

2000

February 1, 2000

Mel McLaughlin Company

Upper Marlboro

 | 

Prince George’s

 County

Project:

Heat Exchange System

Principal Investigator:

Seong
 
Lee
Professor & Lab Director

Technologies:

Fluid Mechanics / Hydrodynamics

MIPS Round 

25

February

 

2000

February 1, 2000

MedImmune, Inc.

Gaithersburg

 | 

Montgomery

 County

Project:

Characterization of Artificial Antibody

Principal Investigator:

Bradford
 
Braden
Professor, Center for Natural Sciences, Mathematics and Nursing

Technologies:

Biotechnology / Genetic Engineering

MedImmune is the global biologics research and development arm of AstraZeneca, a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of small molecule and biologic prescription medicines. MedImmune is pioneering innovative research and exploring novel pathways across Oncology, Respiratory, Cardiovascular & Metabolic Diseases, and Infection and Vaccines. MedImmune is headquartered in Gaithersburg, Md., one of AstraZeneca’s three global R&D centers, with additional sites in Cambridge, UK and Mountain View, Calif.

MedImmune’s SYNAGIS therapeutic is an FDA-approved prescription injection of antibodies that is given monthly to help protect high-risk infants from severe respiratory syncytial virus, or RSV.

RSV is a common virus that, like the flu, is seasonal and easily spread. Most children will get RSV by the age of two. RSV begins with cold-like symptoms but can spread to the lungs. For babies with certain health conditions, RSV can be very serious.

SYNAGIS is the first monoclonal antibody approved for the prevention of an infectious disease, as well as the first such drug to be safely used in children.

Braden’s work contributed to the structural characterization of SYNAGIS. Braden continued to work with MedImmune on a contractual basis for 15 years. Together, their work resulted in two patents and two published papers.

Patents:
• U.S. Patent# 7,229,618: Crystals and structure of Synagis Fab
• U.S. Patent# 6,955,717: Crystals and structure of Synagis Fab

Papers:
• Soft nanomaterials characterization using low voltage-high contrast electron microscopy and advanced image reconstruction techniques, SPIE Photonics West - BIOS: Biomedical Optics Volume 8954, January 31-February 7, 2014, Raúl E. Cachau, Bradford C. Braden, Jack R. Collins, Igor A. Topol1 and Jose R. Casas-Finet
• Nanoparticles characterization using HDR-NTA image analysis, SPIE Photonics West - BIOS: Biomedical Optics Volume 8954, January 31-February 7, 2014, Raúl E. Cachau, Bradford C. Braden, Jack R. Collins1 and Jose R. Casas- Finet

There were some concrete achievements [resulting from the MIPS project], including two patents on SYNAGIS. One was for the fab fragment domain of the antibody that recognizes the isotope of the virus and prevents infection. The second was for the tail of the antibody that models its complement immune function. Once the antibody binds to the virus, it helps with the recognition binding site for them. Those structures were the subject of U.S., European and world patent applications and issued patents.

MIPS Round 

25

February

 

2000

February 1, 2000

AnthroTronix, Inc.

Silver Spring

 | 

Montgomery

 County

Project:

Robot Toolkit for Rehabilitation

Principal Investigator:

Catherine
 
Plaisant
Senior Research Scientist, University of Maryland Institute for Advanced Computer Studies

Technologies:

Robotics

AnthroTronix is a research and development (R&D) firm specializing in the development of advanced interface technology, product development for wearable computing and robotic control systems, and the design, development, and testing of simulation tools for training applications. The company supplies its R&D services and advanced product development to commercial and government customers. AnthroTronix was founded by Corinna Lathan and Jack Maxwell Vice and distributes products emerging from the company’s R&D projects.

The MIPS research resulted in a patent, which AnthroTronix licensed from the University of Maryland. Subsequently, the next generation of JesterBot became CosmoBot, a robot that interacts with children, both with and without disabilities, to promote educational and therapeutic activities. The current version, CosmoBot V3, was tested in a research study at the Mayo Clinic in Rochester, Minn., and was used in physical therapy with children with disabilities through an NIH-funded project. CosmoBot has been tested with children with a range of abilities, including autism spectrum disorders, Down Syndrome, cerebral palsy, neurodevelopmental disorders, and language developmental disorders. Funding sources have included the National Science Foundation (NSF), National Institutes of Health (NIH), and U.S. Department of Education.

CosmoBot was most recently redesigned in 2013 to include additional degrees of motion in the arms and an improved control system. The CosmoBot character is also part of Cosmo’s Learning Systems, an assistive technology product developed by AnthroTronix, which includes the company’s Mission Control input device and accompanying educational software.

AnthroTronix employs 17 people and has generated over $24 million in revenues through research awards and contracts, from funders such as Lockheed Martin, the National Institutes of Health, National Science Foundation, Department of Education, Defense Advanced Research Projects Agency, U.S. Army, U.S. Navy, and NASA, among others.

In 2014, the company received FDA clearance for its computerized, cognitive test battery, known as DANA™. Offered through a mobile medical application, DANA™ provides clinicians with objective measurements of reaction time (speed and accuracy) to aid in the assessment of an individual’s medical or psychological state. In 2015, AnthroTronix won an Edison Awards™ Gold Award in the Medical Testing & Evaluation Category for DANA™. AnthroTronix was awarded the Washington GovStar “Technology Trailblazer” award in 2016.

The experience and expertise gained in the mHealth field while growing its business and research capabilities in the MIPS program moved AnthroTronix into the digital health field and set it on the path to create other innovative health technologies. One such tool, DANA™, is providing researchers, individuals, and health care providers with a new, fast, and flexible way to track cognitive performance and help with the screening for a variety of health issues. DANA™ is available on Android and iOS, has been scientifically validated, and has been verified by test/retest capability.

MIPS provided us with a great opportunity to work with cutting-edge researchers and was core to our ability to develop products for kids with disabilities, as well as children and adults in a variety of markets.

MIPS Round 

25

February

 

2000

February 1, 2000

CEL-SCI Corporation

Baltimore

 | 

Baltimore City

 County

Project:

Murine Model for AutoImmune Disease

Principal Investigator:

Noel
 
Rose

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

25

February

 

2000

February 1, 2000

Stanley Black and Decker, Inc.

Towson

 | 

Baltimore

 County

Project:

Heat Transfer, Noise and Dust

Principal Investigator:

Seong
 
Lee
Professor & Lab Director

Technologies:

Fluid Mechanics / Hydrodynamics

Black & Decker has been setting the standard for home improvement products since 1910. With roots in Baltimore, Maryland, the company evolved from a small machine shop that invented the first portable electric drill to a global manufacturing and marketing powerhouse. Black & Decker’s product line now includes a broad variety of products for both commercial and residential use.

MIPS Round 

25

 

Vulcan Craft

Silver Spring

 | 

out-of-state

 County

Project:

Machining Speed Optimization

Principal Investigator:

Matthew
 
Davies

Technologies:

Factory Automation

MIPS Round 

25

February

 

2000

February 1, 2000

Lockheed Martin Corporation

Bethesda

 | 

Montgomery

 County

Project:

Satellite Multicast Security

Principal Investigator:

John
 
Baras
Professor

Technologies:

Communications

Headquartered in Bethesda, Md., Lockheed Martin is a global security and aerospace company that employs about 120,000 people worldwide and is principally engaged in the research, design, development, manufacture, integration and sustainment of advanced technology systems, products and services. The corporation’s net sales for 2016 were $47.2 billion.

Lockheed and MIPS have collaborated on a total of eleven projects. Lockheed and Martin Marietta merged in 1995.

MIPS Round 

25

February

 

2000

February 1, 2000

Millennium Inorganic Chemicals

Glen Burnie

 | 

Baltimore

 County

Project:

Phosphorus Pollution Reducing Fertilizer

Principal Investigator:

Gary
 
Felton

Technologies:

Agriculture / Poultry Science

MIPS Round 

25

February

 

2000

February 1, 2000

Aither Engineering

Lanham

 | 

Prince George’s

 County

Project:

Towed Array Shape Management

Principal Investigator:

Balakumar
 
Balachandran
Professor

Technologies:

Instrumentation

MIPS Round 

25

February

 

2000

February 1, 2000

Rocky Gap Lodge & Golf Resort

Cumberland

 | 

Allegany

 County

Project:

Habitat Improvement

Principal Investigator:

Kenneth
 
McKaye

Technologies:

Agriculture / Poultry Science

MIPS Round 

25

February

 

2000

February 1, 2000

Mistral-Security, Inc.

Bethesda

 | 

Montgomery

 County

Project:

Test for Illicit Drugs

Principal Investigator:

Andrew
 
Coop
Professor and Chair

Technologies:

Chemical Engineering / Chemistry

MIPS Round 

25

February

 

2000

February 1, 2000

Covega, Inc.

Jessup

 | 

Prince George’s

 County

Project:

Optoelectronic Packaging

Principal Investigator:

Mario
 
Dagenais
Professor

Technologies:

Laser Technology

Optics

MIPS Round 

25

February

 

2000

February 1, 2000

Stanley Black and Decker, Inc.

Towson

 | 

Baltimore

 County

Project:

Optimization of Power Tool Designs

Principal Investigator:

Shapour
 
Azarm

Technologies:

Computer Aided Design

Black & Decker has been setting the standard for home improvement products since 1910. With roots in Baltimore, Maryland, the company evolved from a small machine shop that invented the first portable electric drill to a global manufacturing and marketing powerhouse. Black & Decker’s product line now includes a broad variety of products for both commercial and residential use.

MIPS Round 

25

February

 

2000

February 1, 2000

NovaScreen Biosciences Corporation

Hanover

 | 

Anne Arundel

 County

Project:

Organization of Hydroytic Enzymes

Principal Investigator:

Ronald
 
Weiner

Technologies:

Biotechnology / Genetic Engineering