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MIPS Round 

43

February

 

2009

February 2, 2009

Resensys LLC

College Park

 | 

Prince George’s

 County

Project:

Hybrid Power Cells for Bridge Health Monitoring

Principal Investigator:

Martin
 
Peckerar
Professor, Department of Electrical and Computer Engineering

Technologies:

Instrumentation

Founded in 2008, the mission of Resensys is to protect infrastructure systems against aging, structural malfunction, and collapse. Resensys offers a cost-effective and scalable solution for the real-time monitoring of important structural state quantities such as stress, strain, fatigue cracks, vibration, etc. Resensys’ solution is based on its patented SenSpot technology, which incorporates novel sensing, energy harvesting and wireless communication technologies into a small, multi-sensor device with more than one decade of battery life.

Resensys now has more than 100 major customers and has acquired more than $5.1 million in combined grant money and sales. The company employs four full-time and five part-time employees. Resensys is seeking approval from state and federal authorities for its sensor technologies.

Resensys’ SenSpot sensors are currently installed on hundreds of major bridges in the U.S. and around the World. In Maryland, more than 20 fracture-critical bridges have been monitored since 2012.

Kalantari is a serial entrepreneur. He also founded the technology behind (and the company) Macrophage, which later became RioRey. He won funding in the University of Maryland $75K Business Plan Competition for both companies.

MIPS is a great vehicle to leverage research and expertise for small companies like us in Maryland.
Resensys’ SenSpot sensors are currently installed on hundreds of major bridges in the U.S. and around the World. In Maryland, more than 20 fracture-critical bridges have been monitored since 2012.

MIPS Round 

43

February

 

2009

February 2, 2009

Fuzbien Technology Institute

Rockville

 | 

Montgomery

 County

Project:

Breast Cancer Biomarker Study using CNT Sensor

Principal Investigator:

Laundette
 
Jones
Assistant Professor

Technologies:

Biotechnology / Genetic Engineering

FTI was established to develop a carbon-nano-tube (CNT) based platform technology (CNT-p) for the detection of disease proteins, health markers, and environmental molecules. This CNT-based platform may result in detection with high-sensitivity and very low cost, making it affordable for the general public and thus could reform the preventive medicinal system in the future. FTI will develop the modality of detection and diagnosis for selective protein and molecular recognition of a target analyte in collaboration with nearby university, government labs and other industries.

The process was developed and used for the mouse model study of breast cancer at UMB by Dr. Jones and Fuzbien Technology Institute Inc., and led to a convincing result of this concept in detecting breast cancer. A next-generation device prototype for a diabetes detector using salivary glycated Albumin resulted.

MIPS Round 

43

January

 

2009

January 28, 2009

Juxtopia, LLC

Baltimore

 | 

Baltimore City

 County

Project:

An Auditorily-Based Speech Enhancement Scheme

Principal Investigator:

Carol
 
Espy-Wilson
Professor, Department of Electrical and Computer Engineering and Institute for Systems Research

Technologies:

Electrical / Power Engineering

The Juxtopia Group Inc. is a 501c(3) not-for-profit organization established in 2000 and founded by Jayfus Tucker Doswell. Juxtopia®’s core business is developing human performance products, with a focus on augmented reality headsets and software services where speech is the primary human computer interface.

Juxtopia® developed a speech enhancement product based on this algorithm, which eliminated noise from speech signals. Juxtopia® planned to integrate the noise-reduction software product into its headset and license it to other headset manufacturers and speech service vendors. The company also attracted several SBIR/STTR grants from the National Science Foundation (NSF) and National Institutes of Health (NIH), as well as NASA and the Department of Defense (DOD), to advance its Juxtopia® wearable augmented reality for improving human performance®.

With MIPS funding, Juxtopia was able to collaborate with UMD’s department of electrical engineering to advance its wearable augmented (AR) reality products and get a head start in the market years before Google, Microsoft, and Epson. Securing MIPS funding was not easy by any means and took years. However, the experience helped exercise Juxtopia’s spirit of perseverance and concentrated focus to achieve a tangible result at the end of the MIPS funding.

MIPS Round 

43

February

 

2009

February 2, 2009

SullyPower (ProParts, LLC)

Annapolis Junction

 | 

Baltimore City

 County

Project:

3D Helix Wind Turbine

Principal Investigator:

Jewel
 
Barlow
Director of Glenn L. Martin Wind Tunnel

Technologies:

Energy

Wind Tunnel / Rotor Testing

MIPS Round 

43

February

 

2009

February 2, 2009

AviHome LLC

Salisbury

 | 

Wicomico

 County

Project:

Plenum Floor Ventilation for Poultry House

Principal Investigator:

Jeannine
 
Harter-Dennis
Associate Professor

Technologies:

Agriculture / Poultry Science

MIPS Round 

43

February

 

2009

February 2, 2009

Innovative Biosensors, Inc.

Rockville

 | 

Montgomery

 County

Project:

Microfluidic Sample Preparation for GBS Detection

Principal Investigator:

Pamela
 
Abshire
Professor

Technologies:

Medical Instrumentation / Equipment

MIPS Round 

43

February

 

2009

February 2, 2009

Gliknik Inc.

Baltimore

 | 

Baltimore City

 County

Project:

A drug screening assay to find a drug for lupus

Principal Investigator:

Dean
 
Mann
Professor

Technologies:

Biotechnology / Genetic Engineering

Gliknik is a privately held biopharmaceutical company working to ease human suffering by creating new therapies for people living with cancer and immune disorders. Stradomers™ are the company’s first core innovative discovery; this technology was advanced under the MIPS project. MIPS Project Challenge Intravenous immunoglobulin (IVIG) is used therapeutically in dozens of autoimmune diseases and is in chronic short supply. This project was designed to identify and advance a recombinant human protein that is one of the most active fractions of IVIG, a blood product that was already known to be safe and effective but which currently comes from the pooled blood of tens of thousands of people. The most active component of this product, the Fc portion of aggregates, had been identified in publications. Gliknik invented the concept of treating autoimmune diseases with recombinant products containing multiple Fc, and selected GL-2045 as its first internally generated drug candidate, which it provided to Strome’s lab for in vitro function testing and confirmation of binding affinity to its cognate receptors. The product was later tested by Gliknik for in vivo activity in mouse models of autoimmunity. The result would be the defining of a lead pre-clinical compound to address autoimmune diseases.

MIPS Round 

43

February

 

2009

February 2, 2009

Foligo Therapeutics, Inc.

Rockvile

 | 

Montgomery

 County

Project:

Folate Receptor Targeting for Cancer Treatment

Principal Investigator:

William
 
Bentley
Professor

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

43

February

 

2009

February 2, 2009

Recovery Science LLC

Hollywood

 | 

Saint Mary’s

 County

Project:

Exoskeletal Training for Variable Disease States

Principal Investigator:

Jae Kun
 
Shim
Assistant Professor

Technologies:

Medical Instrumentation / Equipment

MIPS Round 

43

February

 

2009

February 2, 2009

TRX Systems, Inc.

Greenbelt

 | 

Prince George’s

 County

Project:

Product Life Cycle Assessment of TRX Sentinel

Principal Investigator:

Francis
 
McCluskey
Professor

Technologies:

Reliability

TRX Systems delivers GPS-denied location software and solutions. TRX is the first company to use sensor fusion and the dynamic mapping of structural, magnetic, and RF features to pinpoint location indoors, underground, and in dense urban areas. The company’s NEON® location solutions use low-cost MEMS sensors, combined with higher level mapping algorithms, to deliver accurate 3D location, including the elevation of personnel within buildings.

The two-phase project resulted in a design for TRX’s tracking accessory enclosure. While the packaging has evolved, the basic design and materials were developed during the project.

TRX has received $2.9 million in funding through three investment rounds from four investors, including New Dominion Angels, the Maryland Department of Business and Economic Development, Motorola Solutions Venture Capital, and several other strategic and private investors.

The company has released three products, all of which use the NEON location solutions ability to locate and map where GPS is unavailable or unreliable, such as indoors and underground:

• Personnel Tracker, a comprehensive indoor location solution delivering team situational awareness and tracking for security, public safety, and enterprise users.

• Signal Mapper, which offers automated geo-referencing and 3D visualization for test and measurement applications, including Land Mobile Radio (LMR), cellular (LTE), WiFi, BLE, radiation, and other sensor mapping.

• Squad Tracker, which provides a resilient indoor and outdoor GPS-denied location and navigation solution for the dismounted soldier.

In February, 2017, Houston police used the TRX NEON Personnel Tracker Solution to help ensure public safety in NRG Stadium for Super Bowl LI. The NEON solution used the Harris County Public Safety Broadband network at NRG Park and allowed each officer to be tracked in 3D from the command center throughout the nearly 2 million square feet of NRG Stadium. GPS could not be used since the roof over the stadium was closed during the game.

Additional Mtech/UMD Programs Utilized:
Technology Advancement Program (TAP)

MIPS helped my company deliver a product with the robustness required by our public safety, defense, and industrial customers, who operate in the most challenging environmental conditions.

MIPS Round 

43

February

 

2009

February 2, 2009

Sirnaomics, Inc.

Gaithersburg

 | 

Montgomery

 County

Project:

Silencing Scar Formation by Targeting Hoxb13

Principal Investigator:

A.
 
Mixson
Assistant Professor

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

43

February

 

2009

February 2, 2009

Emerald Sky Technologies LLC

Columbia

 | 

Howard

 County

Project:

H-OZ Collaborative Autopilot Inner Loop Controller

Principal Investigator:

James
 
Humbert
Assistant Professor

Technologies:

Aerodynamics / Aerospace Engineering

MIPS Round 

43

February

 

2009

February 2, 2009

Cellex, Inc.

Rockville

 | 

Montgomery

 County

Project:

A Rapid and Sensitive Flu Test

Principal Investigator:

Richard
 
Zhao
Professor, Pathology, University of Maryland School of Medicine

Technologies:

Biotechnology / Genetic Engineering

Cellex is a medical device company dedicated to developing innovative technologies that enable assays to be fast, accurate, sensitive, easy-to-use and inexpensive. The company’s current focus includes a homogeneous biochemiluminescent assay (HBA) technology, HBA-based assays and easy-to-use instruments.

This MIPS project enabled Cellex to gather clinical data, which helped the company get a $2 million NIH grant, which in turn permitted the company to perform a large clinical study enrolling more than 500 patients. The data from the MIPS and NIHfunded studies was submitted to the FDA in September, 2012, in an application for approval for Cellex’s first product, the QFlu Combo Test, which can be used to simultaneously diagnose influenza and detect resistance to Tamiflu. This is a first-of-its-kind product that has commercial potential and public health implications.

Other than the qFLU combo Test, the assay was also configured into a diagnostic-use only test, the qFLU Dx Test. The qFLU tests are the only tests that do not detect viral proteins (antigens) or nucleic acids, and are less susceptible to genetic changes of flu viruses. Both the qFLU Combo Test and qFLU Dx Test have now been CE-marked.

The MIPS grants have played an important role in bringing the QFlu project to a successful conclusion.
Working with BD (Becton, Dickinson and Co.), the qFLU Combo Test was awarded another grant by the Biomedical Advanced Research and Development Authority (BARDA). The award supports the clinical evaluation of the assay for its use in global influenza surveillance. The regional rights of these qFLU assays were licensed to third parties in various regions. The qFLU Dx Test is particularly suited for markets with dense populations such as China, as the assay is rapid, can be performed in large batches, and uses simple instruments.

MIPS Round 

43

February

 

2009

February 2, 2009

Coil, LLC

College Park

 | 

Howard

 County

Project:

Novel Signal-Processing Prototypes

Principal Investigator:

Patrick
 
O'Shea
Professor and Chair

Technologies:

Computer Hardware Design

MIPS Round 

43

February

 

2009

February 2, 2009

Syan Biosciences LLC

Laytonsville

 | 

Montgomery

 County

Project:

Protein Chip Prototype Development

Principal Investigator:

Gregory
 
Payne
Director

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

42

August

 

2008

August 1, 2008

Rafagen, Inc.

Rockville

 | 

Montgomery

 County

Project:

Super Promoters for Therapeutic Protein Production

Principal Investigator:

Daniel
 
Kuebbing
Director

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

42

August

 

2008

August 1, 2008

Ocean Equities, LLC

Annapolis

 | 

Anne Arundel

 County

Project:

Recirculating Aquaculture System for Oysters

Principal Investigator:

Yonathan
 
Zohar
Chairman

Technologies:

Aquaculture

MIPS Round 

42

August

 

2008

August 1, 2008

Neuronascent, Inc.

Clarksville

 | 

Howard

 County

Project:

Neurogenic Agent's Effect on Ischemic Injury

Principal Investigator:

Gary
 
Fiskum
Professor and Vice Chair, Research

Technologies:

Biotechnology / Genetic Engineering

MIPS Round 

42

August

 

2008

August 1, 2008

Medcura, Inc.

College Park

 | 

Prince George’s

 County

Project:

Self-Assembled Dressings for Active Wound Care

Principal Investigator:

Srinivasa
 
Raghavan
Professor, Department of Chemical and Biomolecular Engineering

Technologies:

Biotechnology / Genetic Engineering

Medcura (formerly gel-e Inc.), a privately held, clinical-stage medical device company, develops a broad range of hemostatic and wound treatment products, including bandages for the treatment of routine cuts and scrapes, foams and putties for traumatic and military injuries, and surgical gels and powders.

Medcura simply would not be alive and thriving without the support of MIPS. Our 2008 MIPS grant was the first substantial research grant that we received, and that funding has created a platform for our company to raise over $1.7 million in non-dilutive funding and reach a first regulatory milestone. Medcura hopes to continue to serve as an example of a real-world manifestation of the vision for the MIPS program.

MIPS Round 

42

August

 

2008

August 1, 2008

Refractory Composites, Inc.

Glen Burnie

 | 

Anne Arundel

 County

Project:

Gel Fuel Development

Principal Investigator:

Srinivasa
 
Raghavan
Professor

Technologies:

Chemical Engineering / Chemistry

MIPS Round 

42

August

 

2008

August 1, 2008

Traffax Inc.

College Park

 | 

Queen Anne’s

 County

Project:

TRAFFAX Traffic Detector Design and Testing

Principal Investigator:

Ali
 
Haghani
Professor, Chairman

Technologies:

Instrumentation

MIPS Round 

42

October

 

2008

October 1, 2008

Instant Access Networks, LLC

Cumberland

 | 

Allegany

 County

Project:

EMP-protected Microgrids Using Renewable Energy

Principal Investigator:

Hilkat
 
Soysal
Lecturer

Technologies:

Electrical / Power Engineering

MIPS Round 

42

August

 

2008

August 1, 2008

American Dynamics Flight Systems, Inc.

Jessup

 | 

Howard

 County

Project:

AD-150 VTOL UAS Flight Dynamics Modeling

Principal Investigator:

James
 
Humbert
Assistant Professor

Technologies:

Aerodynamics / Aerospace Engineering

MIPS Round 

42

August

 

2008

August 1, 2008

Maxion Technology Inc.

Jessup

 | 

Howard

 County

Project:

High Power Interband Cascade Lasers

Principal Investigator:

Mario
 
Dagenais
Professor

Technologies:

Laser Technology

MIPS Round 

42

August

 

2008

August 1, 2008

Aparna Biosciences

Rockville

 | 

Montgomery

 County

Project:

Therapy of Candida with HK-fluconazole conjugates

Principal Investigator:

A.
 
Mixson
Assistant Professor

Technologies:

Biotechnology / Genetic Engineering